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Brain cancer occurs in about 7 out of every 100,000 people. Is your risk reduced from that? No. Is it reduced from keeping it plastered to your ear? Maybe. Some researchers think there maybe a link between cell phones and brain cancer, but no one knows yet. Keeping a cell phone in a shirt pocket could cause injury if you have a pacemaker.
I think it depends what it looks like. But it is not only for holding your phone but also ideal for protecting your mobile phone. So I think it is necessary.
You can try, but not likely. You're better off designing a purse. More women would go for that. Besides, I think yours has already been designed.